Two sample MR report
CD52_Monocyte (Mono) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 16 | -0.0591291 | 0.0454210 | 0.2139972 |
| Weighted median | 16 | -0.0405510 | 0.0122359 | 0.0009194 |
| Inverse variance weighted | 16 | -0.0321282 | 0.0093743 | 0.0006097 |
| Simple mode | 16 | -0.0436574 | 0.0145767 | 0.0090644 |
| Weighted mode | 16 | -0.0401592 | 0.0134607 | 0.0092804 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 10.28752 | 14 | 0.7408746 |
| Inverse variance weighted | 10.65663 | 15 | 0.7765341 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0157909 | 0.0259915 | 0.5532209 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006052 | 0 | TRUE | 0.0193984 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
